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Class of Compound: Peptide Mechanism of Action: BPC-157 is known to stimulate vascular endothelial growth factor, which triggers the formation of blood vessels. Also, it blocks the growth-inhibiting action of 4‐hydroxynonenal. Further, it upregulates multiple growth receptors in the body and stimulates the production of fibroblasts, vital to the synthesis of collagen. Notable Studies: Pentadecapeptide BPC 157 and the central nervous system Fistulas healing. Stable gastric pentadecapeptide BPC 157 therapy BPC 157 counteracts QTc prolongation induced by haloperidol, fluphenazine, clozapine, olanzapine, quetiapine, sulpiride, and metoclopramide in rats What is BPC-157? BPC-157 refers to Body Protection Compound-157, a naturally occurring peptide found in human stomach juices. Composed of a sequence of 15 amino acids, the peptide can also be found in trace amounts in the gastric fluids of other mammals. The peptide plays a fundamental role in preserving the lining of the GI tract. However, researchers are interested in its application in other areas of the body—particularly in regards to wound healing, neuroprotection, and muscle and tissue growth. M ...
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What is Tirzepatide? Tirzepatide is a synthetic peptide that acts as a dual agonist at the glucose-dependent insulin secretagogue polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. The compound has been studied for its potential to affect glucose regulation and energy balance. Researchers are particularly interested in Tirzepatide because of its potential role in treating metabolic disorders, including those associated with insulin resistance and excess weight. How does Tirzepatide work? Tirzepatide is designed to activate both GIP and GLP-1 receptors, which are involved in regulating insulin secretion and glucose homeostasis. By stimulating these receptors, Tirzepatide can enhance insulin secretion in response to elevated blood glucose, inhibit glucagon release, and slow gastric emptying. In addition, this dual agonist effect may help reduce appetite and caloric intake by acting on receptors within the central nervous system, which may be beneficial for weight management. What are the potential benefits of Tirzepatide? Research suggests that Tirzepatide may offer several potential benefits: Improved blood sugar control: Tirzepatide ...
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What is Hexarelin? Hexarelin is a synthetic hexapeptide that mimics ghrelin, the body’s natural gut hormone. It acts on the growth hormone secretagogue receptor (GHS-R) to trigger the release of growth hormone . The growth hormone release resulting from hexarelin treatment can improve the body’s ability to produce collagen, repair ligaments and tendons, grow muscle fibers, reduce visceral body fat, and increase bone density . While hexarelin is a ghrelin analog, studies have found that hexarelin is a superior alternative to ghrelin therapy because of its potency and stability, particularly as a cardioprotective agent. The administration of hexarelin has also been shown to provide neuroprotective benefits such as promoting the growth of new brain cells, protecting healthy brain cells, and reducing inflammation in the brain. Hexarelin Benefits and Uses Hexarelin is frequently sought out for its marked effects on fat loss and muscle-building. Its ability to affect insulin sensitivity, energy production, and lean muscle growth makes it an attractive compound for researchers wishing to enhance the body composition of their subjects. Hexarelin for Fat Reduction ...
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What is Hexarelin? Hexarelin is a synthetic hexapeptide that mimics ghrelin, the body’s natural gut hormone. It acts on the growth hormone secretagogue receptor (GHS-R) to trigger the release of growth hormone . The growth hormone release resulting from hexarelin treatment can improve the body’s ability to produce collagen, repair ligaments and tendons, grow muscle fibers, reduce visceral body fat, and increase bone density . While hexarelin is a ghrelin analog, studies have found that hexarelin is a superior alternative to ghrelin therapy because of its potency and stability, particularly as a cardioprotective agent. The administration of hexarelin has also been shown to provide neuroprotective benefits such as promoting the growth of new brain cells, protecting healthy brain cells, and reducing inflammation in the brain. Hexarelin Benefits and Uses Hexarelin is frequently sought out for its marked effects on fat loss and muscle-building. Its ability to affect insulin sensitivity, energy production, and lean muscle growth makes it an attractive compound for researchers wishing to enhance the body composition of their subjects. Hexarelin for Fat Reduction ...
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Compound Class: Peptide Mechanism of Action: CJC-1295 binds to receptors in the pituitary gland, stimulating the release of plasma growth hormone (GH) and insulin-like growth factor 1 (IGF-1). Notable studies: CJC-1295, a long-acting GH-releasing hormone analog, stimulates growth hormone (GH) and insulin-like growth factor I secretion in healthy adults over a long period of time Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, restores growth to normal in GHRH knockout mice Sleep and endocrine changes after intranasal administration of growth hormone-releasing hormone in adolescents and older adults Also known as: UNII-62RC32V9N7, 62RC32V9N7 Research applications: Growth hormone deficiency Body composition Sleep quality; anti-aging Risks: Limited human data Lack of FDA approval WADA banned list Chemical structure CJC-1295 structure What is CJC-1295? CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) and growth hormone secretagogue (GHS) developed by ConjuChem Technologies in the mid-2000s. Originally designed to treat obe ...
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Compound Class: Peptide Mechanism of Action: CJC-1295 binds to receptors in the pituitary gland, stimulating the release of plasma growth hormone (GH) and insulin-like growth factor 1 (IGF-1). Notable studies: CJC-1295, a long-acting GH-releasing hormone analog, stimulates growth hormone (GH) and insulin-like growth factor I secretion in healthy adults over a long period of time Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, restores growth to normal in GHRH knockout mice Sleep and endocrine changes after intranasal administration of growth hormone-releasing hormone in adolescents and older adults Also known as: UNII-62RC32V9N7, 62RC32V9N7 Research applications: Growth hormone deficiency Body composition Sleep quality; anti-aging Risks: Limited human data Lack of FDA approval WADA banned list Chemical structure CJC-1295 structure What is CJC-1295? CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) and growth hormone secretagogue (GHS) developed by ConjuChem Technologies in the mid-2000s. Originally designed to tre ...
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Compound Class: Peptide Mechanism of Action: Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist that triggers and stimulates growth hormone production by mimicking ghrelin. It binds to ghrelin receptors, stimulating growth hormone release, and inhibits somatostatin and suppresses its effects. Notable Studies: · Ipamorelin, the first selective growth hormone secretagogue · The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced reductions in bone formation in adult rats · The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats What is ipamorelin? Ipamorelin is a laboratory-made compound known as growth hormone-releasing peptide. It stimulates the body to release growth hormone, which promotes systemic growth of muscle, bone, vascular system, and other cells and body tissues. Ipamorelin is unique among growth hormone-releasing peptides in that, unlike most growth hormone-releasing peptides, it does not activate the body's natural stress response. This gives ipamorelin an advantage over similar compounds. However, research on ipamorel ...
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What is TB-500? TB-500 is a 43 amino acid synthetic analog of thymosin B-4 (TB-4), which occurs naturally in nearly all mammalian cells. TB-500 is known for its effects on actin, cell migration, and wound healing. Animal models and in vitro studies have shown that TB-500 can improve blood vessel growth, accelerate wound healing, reduce inflammation, and promote production of extracellular matrix. The peptide is currently being studied for its ability to reduce oxidative stress in spinal cord injuries, improve recovery after heart attacks, and have a variety of anti-aging effects. TB-500 Mechanism of Action TB-500 is the active domain of TB-4 and primarily acts as an actin-binding protein. Actin is an important component of cellular structure and makes up microfilaments. Microfilaments are responsible for giving cells their shape, protecting the integrity of cell membranes, allowing cells to move/migrate, and certain steps in cell reproduction. Actin is also one of the main components of muscle protein. Without actin, muscles cannot contract. Actin-binding proteins such as TB-4 sequester actin monomers (single units of actin), thereby protecting them from degradation and allowing them to polymerize into microfi ...
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S23 S23 is an oral selective androgen receptor modulator (SARM). The drug was originally developed by GTX Inc. as a male hormonal contraceptive. It has a high affinity for the androgen receptor with a Ki value of 1.7 nM. A study published by Jones et al. compared the effectiveness of S23 in castrated and uncastrated male rats. Effects of S23 on Fertility In castrated male rats, S23 was effective at doses of 0.43 mg/day in the prostate and 0.079 mg/day in the levator ani muscles. In intact male rats, doses above 0.1 mg/day resulted in greater than 50% suppression of luteinizing hormone (LH). This dose was associated with a decrease in prostate size and an increase in levator ani muscle size. In a study of intact male subjects treated with S23 and estradiol benzoate (to maintain sexual activity), sperm was not found in the testes of 4 of 6 subjects after 10 weeks. Furthermore, none of the six experimental animals reported pregnancy. After treatment, infertility was completely reversible; all subsequent mating trials resulted in pregnancy . Effects of S23 on Muscle Mass and Body Fat The effects of S23 on muscle ma ...
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Information about Metribolone Metribolone, chemically known as Mmethyltrienolone, is a synthetic, orally active anabolic androgenic steroid (AAS) derivative of 17α-alkylated nandrolone (19-nortestosterone) that has never been marketed for human use but has been used extensively in research and underground bodybuilding. Investigated as a thermal ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR. More precisely, Metribolone is a 17α-methylated derivative of Trenbolone. It was briefly studied in the late 1960s and early 1970s for the treatment of advanced breast cancer in women, but was found to cause signs of severe hepatotoxicity at very low doses, so development of the drug was discontinued. Metribolone Pharmacology Metribolone is an anabolic androgenic steroid (AAS) or AR agonist with both anabolic and androgenic activity. It is one of the most potent AAS synthesized to date, with oral anabolic activity 120 to 300 times that of the reference AAS methyltestosterone and androgenic activity 60 to 70 times that of the reference AAS methyltestosterone in ovariectomized male rats, although the same level of effectiveness has not been ...
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Description Epistane 10MG/TABS 100 TABS is a prohormone that is popular among athletes and bodybuilders for its anabolic and androgenic effects. It is a synthetic form of dihydrotestosterone that converts to methyldihydrotestosterone after oral administration. It can increase muscle mass, strength, and increase libido. Effective in improving endurance and reducing fatigue. Epistane can be used alone or in combination with other supplements or prohormones. Many people use Epistane with testosterone to increase anabolic effects and increase muscle mass and strength. The dosage of Epistane varies depending on individual needs and goals, but the recommended dosage for adult males is 20 to 30 mg per day. It is recommended to use the prohormone for 4 to 6 weeks, after which a break should be taken before the next cycle. There are many benefits that can be gained from using Epistane, such as: Muscle Mass Increase: Epistane is a potent prohormone that can increase muscle mass by increasing protein synthesis. Increase in Strength: Epistane can help increase strength by increasing nitrogen retention in the muscles, which helps with muscle development. Improves libido: Epistane is an androgen, which means it can inc ...
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Description Estradiol valerate (EV) is an estrogen medication. For women, it is used as hormone therapy to treat menopausal symptoms and low estrogen levels, hormone therapy for transgender women, and hormonal contraception. It is also used to treat prostate cancer in men. The medication is taken orally or injected into muscle or fat every 1 to 4 weeks. Uses Estradiol valerate is a female hormone (estrogen). It is used to relieve menopausal symptoms, including vaginal dryness, hot flashes, and more. Menopausal symptoms occur because the body produces less estrogen; with EV, these symptoms are minimized. This medication can also help women with ovarian failure, hypogonadism, and women to produce enough estrogen, and men can also use it to treat prostate cancer (for palliative purposes only). Indications Estradiol valerate is marketed as an intramuscular injection under the trade name Delestrogen for the treatment of moderate to severe vasomotor symptoms and vulvovaginal atrophy associated with menopause, for the treatment of estrogen deficiency due to hypogonadism, castration, or primary ovarian failure, and for the treatment of advanced androgen-dependent prostate cancer (for palliative treatment only). Estr ...
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Halotestin Function and Properties: Fluoxymesterone is a testosterone-derived anabolic androgenic steroid, more specifically a structurally altered form of methyltestosterone. Fluoxymesterone is a testosterone hormone that has had a methyl group added to the 17th carbon position to allow for oral administration. It also has a fluorine group added to carbons 9 and 3, and a hydroxyl group added to carbon 11. These modifications inhibit aromatization of the steroid, greatly increasing its androgenic properties. The androgenic properties and activity of fluoxymesterone will far exceed those of methyltestosterone. Based on its structural design, Halotestin has an anabolic rating of 1,900 and an androgenic rating of 850. All ratings are benchmarked against pure testosterone, which has a rating of 100 in both categories. This means that Halo, as it is often called, has a rating that is almost beyond reasonable, but its anabolic rating is extremely deceptive. While its anabolic rating is high, its anabolic conversion in the human body appears to be close to zero. This steroid does not produce any significant anabolic effects at all, and works primarily through androgenic activity. Halotestin has some very powerful effects, the ...
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Functions and Properties of Turinabol: Oral Turinabol is formally known as 4-chlorodehydromethyltestosterone, which is essentially a structurally altered form of Dianabol (Methandrostenolone), which itself is a derivative of testosterone. The structural composition of Oral Turinabol is very simple. The compound is simply the testosterone hormone with double bonds added at carbons 1 and 2, which changes the anabolic to androgenic ratio in favor of anabolics. It also adds a chlorine group at carbon 4, which inhibits aromatization of the hormone and further reduces its androgenic properties. The final change is the addition of a methyl group at the 17th carbon position, which protects the hormone from oral administration. This final change officially classifies Oral Turinabol as a C17-alpha alkylated (C17-aa) anabolic androgenic steroid. Functionally, the properties of Oral Turinabol are very simple. Like most anabolic steroids, it should have a positive effect on protein synthesis and nitrogen retention, as well as increase red blood cell count. These properties are all important because they enhance the anabolic environment of the individual. Protein synthesis is a major component of muscle, synthesis represents the rate at whi ...
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Describe Superdrol is an anabolic steroid that has a unique history compared to many anabolic steroids. Superdrol itself is simply the brand name of an over-the-counter anabolic steroid marketed by Anabolic Extreme as a prohormone or nutritional supplement. Although an anabolic steroid, the active hormone, methylandrosterone, was never listed on the US controlled substances list, and in 2005, it appeared on the shelves of most major supplement companies and was a huge success. However, due to intense pressure from the FDA, Superdrol was discontinued in 2006. While the Superdrol brand was short-lived, over-the-counter and black market methylandrosterone continued to appear around the world until mid-2012. In 2012, methylandrosterone was added to the US controlled substances list and classified as a Schedule III controlled substance along with all anabolic steroids. Superdrol Function and Features: Superdrol is an anabolic androgenic steroid composed of the active steroid hormone methylandrosterone. This is a dihydrotestosterone (DHT) derived anabolic steroid, more specifically a structurally altered androgen ketone. Superdrol is simply an androgen ketone with a methyl group added to the 17th carbon pos ...
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Stanozolol Ingredients Stanozolol is a derivative of dihydrotestosterone, but doctors generally consider its activity and reaction time to be milder than androgens. You can feel it showing a greater tendency to muscle growth compared to androgenic activity. Stanozolol does provide the best muscle growth, and at the same time, the anabolic properties in this ingredient are mild compared to other compounds. Usually people feel their muscles become firmer and they remain so after stopping the use of stanozolol. You can use a protein-rich diet to keep your muscles getting leaner and firmer. Structure of Stanozolol When you talk about the structure of stanozolol, you will find that it has a structure that cannot be converted into estrogen. With stanozolol, you do not need to worry about water retention caused by estrogen because stanozolol provides a perfect physique and perfect muscles. When you do not want muscle growth to lead to excessive weight, you will find this drug very useful in increasing the raw mass of muscles. Athletes use this anabolic steroid because of its excellent qualities. Dosage of Stanozolol The dosage of stanozolol for men and women varies greatly. The dosage for men is usually 20 to 100 m ...
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Key Features of DHB - Tn Pharma Dihydroboldenone (DHB), also known as 1-testosterone, is a synthetic anabolic steroid that is a derivative of testosterone. 1-Testosterone is characterized by its strong anabolic effects, which means that it increases protein synthesis in the body, which translates into an increase in muscle mass. It also has a relatively low aromatization to estrogens, which means there is less risk of side effects associated with water retention and gynecomastia. Compared to testosterone, dihydroboldenone is more anabolic and less androgenic, ensuring improved performance and strength. Effective in improving whole-body strength and enhancing muscle growth. Anabolic and Androgenic Properties: DHB is a stronger anabolic agent than testosterone, but with less androgenic activity! This means that it can stimulate muscle growth while reducing side effects associated with androgenic responses, such as acne, baldness, or excessive body hair growth. Strength and Endurance: Users of DHB often notice increases in strength, lean muscle mass, and improved endurance, making it a top choice for athletes who want to improve their performance without excessive weight gain. Benefits: In ...
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Side effects of Trestolone (MENT+) Side effects of Trestolone include low estrogen levels and related symptoms such as decreased sexual function and decreased bone mineral density. Due to its androgenic and progestogenic activity, Trestolone has antigonadotropic effects. These effects lead to a reversible inhibition of sperm production and cause Trestolone to have a contraceptive effect in men. It takes 5-6 months after stopping the medication for normal sperm production to return to normal. The drug has weak estrogenic activity. Dosage and use of Trestolone - MENT Trestolone acetate has been shown to increase levels of growth hormone and IGF (insulin-like growth factor), eliminate libido problems, and give beast-like strength and muscle mass - weight gains of the order of 20-25 kg are quite possible with a cycle of Trestolone (MENT+ Tn Pharma). A standard dose of MENT once or twice a week is reasonable (250 mg - 1 ml). Steroid cycles should not exceed 10 weeks and are perfect in combination with testosterone. Benefits and Uses of Trestolone MENT+ MENT is the first androgen to promote health (i.e. reduce the incidence of prostate disease). Clinicians can also use MENT to treat hypogonadism, prost ...
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Syn Pharma Primosyn 100 (Methenolone Enanthate) Me thenolone is a derivative of dihydrotestosterone (DHT) or more specifically a structurally altered version. The composition of the hormone is DHT with an added double bond at carbon positions one and two. This greatly increases the steroid’s anabolic nature. ...
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When used in a muscle-building regimen, Trenbolone Base will give you extraordinary gains in muscle mass and strength. There is no risk of side effects associated with high estrogen. Trenbolone Base also has an extremely powerful effect on burning subcutaneous fat by directly stimulating lipolysis. The use of Trenbolone Base carries a significant risk of androgenic side effects, as the hormone is so powerful, and there is a risk of Trenbolone-specific side effects, including insomnia, night sweats, panic, and aggression… insomnia, night sweats, panic, and aggression. ...
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TestosteroneTestosterone Synthetic testosterone was synthesized in 1935 by German biochemist Adolf Butenandt and Swiss chemist Leopold Ruzicka, both of whom received the Nobel Prize for this work. Testosterone is the main sex hormone in men, it directly affects the development of the testicles and prostate, has a great influence on the formation of muscle tissue, bone density and strength. In addition, testosterone is largely responsible for dozens of functions in the human body: general health, well-being, enhanced libido, energy, immunity, prevention of osteoporosis (loss of bone density) and possible protection against heart disease. Studies have shown that maintaining higher testosterone levels in older men improves many parameters that are thought to reduce the risk of cardiovascular disease, such as increased lean body mass, reduced visceral fat mass, lower total cholesterol and blood sugar control. It not only determines sex differences, but also, for example, regulates the number of thromboxane A2 receptors on megakaryocytes and platelets, thereby regulating platelet aggregation in humans. It is responsible for behavior, mood, romantic relationships and, reportedly, even influences the choice of its carriers. Research ...
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Describe Sustanon is a popular testosterone blend and is without a doubt the most popular and well-known blend of all time. Sustanon is manufactured by Organon with the idea of combining the best of both small (short) ester and large (long) ester testosterone into a single compound. This would allow individuals to maintain steady testosterone hormone blood levels with an infrequent injection schedule while reaping the benefits of fast-acting results. The limited injection frequency makes Sustanon the perfect compound for treating low testosterone. It allows individuals to maintain steady levels without having to constantly stick themselves with a needle, but that is really the only advantage this testosterone has. For athletic athletes, Sustanon will not offer any advantages over the monoester testosterone compound. In terms of athletic performance, we will find that if an individual wants to maintain not only steady blood levels, but peak blood levels, he will still need to inject the hormone frequently. Many people often mistakenly believe that Sustanon is superior to the monoester testosterone form because it carries four different testosterones in one injection. As for the basic functio ...
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Testosterone Base is 100% pure testosterone, similar to an oil-based testosterone suspension, but Test Base is technically a solution rather than a suspension. Test Base contains no visible testosterone crystals, as they are found in an oil and solvent solution, not water. There are no crystals to slowly absorb into the injection site. Therefore, when you inject Test Base, blood testosterone levels rise quickly and fall faster than with a standard aqueous testosterone suspension. Test Base gives a huge immediate hit after injection, and is arguably the fastest testosterone product available today. Another advantage of Test Base is that you can use a very small needle to inject it. There are no crystals in Test Base to clog the needle, so it can be injected with an insulin syringe. Test Base is ideal for pre-training or weightlifting or strength sports. I recommend injecting Test Base two hours before training to increase aggression and power Testosterone Base is an injectable steroid that contains testosterone, but does not contain any esters. It is pure testosterone without any esters, so esters are not counted in the weight. 100 mg of testosterone ester is equal to 100 mg minus the weight of the ester, while 100 mg of testosterone ...
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Indications/Use Testosterone replacement in primary and secondary male hypogonadism. Dosage/Instructions for Use Dosing Regimen: Testosterone undecanoate (Nebido) is injected once every 10 to 14 weeks (1 vial is equivalent to 1000 mg of testosterone undecanoate). Injections at this frequency maintain adequate testosterone levels without causing accumulation. Injections must be given very slowly. Testosterone undecanoate (Nebido) is strictly for intramuscular use. Special care must be taken to avoid intravascular injection. Additional Information for Special Populations: Pediatric Patients: Testosterone undecanoate (Nebido) is not indicated for use in children and adolescents and has not been clinically evaluated in males under 18 years of age Geriatric Patients: Limited data suggest that no dose adjustment is required in elderly patients Patients with Hepatic Insufficiency: No formal studies have been conducted in patients with hepatic insufficiency. Testosterone undecanoate (Nebido) is contraindicated in men with past or current liver tumors Patients with Renal Insufficiency: No formal studies have been conducted in patients with renal insufficiency. Contraindications ...
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