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Blog Dec 29, 2016

Can Weight Loss Drugs Affect Your Fertility? A Woman’s Guide

In recent years, weight loss drugs have become increasingly popular as many women seek solutions to manage their weight and improve overall health. These medications, ranging from prescription drugs to over-the-counter supplements, promise quick results, but t ...

Blog Naov 19, 2016

Getting the Most Out of Weight Loss Medications: Small Changes, Big Impact

Weight loss medications like Ozempic, Wegovy, and Mounjaro have changed the game for many people struggling with weight loss. They help curb appetite, regulate blood sugar, and make it easier to eat less without feeling like you’re constantly battling hunger. ...

Blog Jan 19, 2016

Weight Loss Without the Burnout: Creating Habits That Actually Last

Losing weight can feel like an uphill battle, especially when you’re constantly told you need to overhaul your entire lifestyle overnight. It’s no wonder so many people start strong, only to crash and burn a few weeks later. Diets that feel like punishment, wo ...

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Melanotan 2

Mechanism of Action: Melanotan II is an agonist of melanocortin receptors 1 and 4 (MC-1R and MC-4R), which respectively regulate melanin production and male erectile function. It is also believed to stimulate MC-3R, which affects appetite and energy levels. Notable Studies: · Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study · Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan 2 · An unhealthy glow? A review of Melanotan use and associated clinical outcomes What is Melanotan 2? Melanotan 2 is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH). The molecule was first developed in the 1980s by University of Arizona researchers, who were looking to clarify the nature and role of the melanocortin receptors in physiological functions. Namely, the peptide was intended to be used as a sunless tanning agent, but was subsequently found to strongly affect sexual function and appetite . Melanotan 2 (MT-II) should not be confused with another ...

TB-500

What is TB-500? TB-500 is a 43 amino acid synthetic analog of thymosin B-4 (TB-4), which occurs naturally in nearly all mammalian cells. TB-500 is known for its effects on actin, cell migration, and wound healing. Animal models and in vitro studies have shown that TB-500 can improve blood vessel growth, accelerate wound healing, reduce inflammation, and promote production of extracellular matrix. The peptide is currently being studied for its ability to reduce oxidative stress in spinal cord injuries, improve recovery after heart attacks, and have a variety of anti-aging effects. TB-500 Mechanism of Action TB-500 is the active domain of TB-4 and primarily acts as an actin-binding protein. Actin is an important component of cellular structure and makes up microfilaments. Microfilaments are responsible for giving cells their shape, protecting the integrity of cell membranes, allowing cells to move/migrate, and certain steps in cell reproduction. Actin is also one of the main components of muscle protein. Without actin, muscles cannot contract. Actin-binding proteins such as TB-4 sequester actin monomers (single units of actin), thereby protecting them from degradation and allowing them to polymerize into microfi ...

OXYTOCIN

What is oxytocin? The peptide hormone is made up of 9 amino acids. It is produced in the hypothalamus, an area of the brain that controls heart rate, blood pressure, and digestion. OT is released into the bloodstream by the posterior pituitary gland. Oxytocin was discovered by Sir Henry Dale in 1996. He found that extracts from the posterior pituitary gland of humans caused the uterus of pregnant cats to contract. Sir Henry Dale also coined the name oxytocin, which means "quick labor" in Greek. This peptide hormone controls many functions. It has an impact on labor, milk secretion during breastfeeding, and bonding with newborns in humans. It also plays an important role in sexual arousal, romantic attachment, and other social interactions. It is also known as the "love hormone." A 2012 study found that levels of this hormone were significantly higher in newly-in-love people than in singles. The findings suggest that it may play an important role in the initial stages of a relationship. Pure Rawz sells this product for research use only. How does oxytocin work? Research suggests that it interacts with neural pathways responsible for processing motivation-related stimuli. In particular, ...

IPAMORELIN

Compound Class: Peptide Mechanism of Action: Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist that triggers and stimulates growth hormone production by mimicking ghrelin. It binds to ghrelin receptors, stimulating growth hormone release, and inhibits somatostatin and suppresses its effects. Notable Studies: · Ipamorelin, the first selective growth hormone secretagogue · The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced reductions in bone formation in adult rats · The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats What is ipamorelin? Ipamorelin is a laboratory-made compound known as growth hormone-releasing peptide. It stimulates the body to release growth hormone, which promotes systemic growth of muscle, bone, vascular system, and other cells and body tissues. Ipamorelin is unique among growth hormone-releasing peptides in that, unlike most growth hormone-releasing peptides, it does not activate the body's natural stress response. This gives ipamorelin an advantage over similar compounds. However, researc ...

MOTS-C

Class of Compound: Peptide Mechanism of Action: While the precise mechanism of action of MOTS-c is currently under investigation, it is hypothesized that its metabolic effects are mediated through its translocation to the nucleus and subsequent activation of AMPK. Notable Studies: · MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. · The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. · MOTS-c Functionally Prevents Metabolic Disorders. Metabolites. What is MOTS-c? MOTS-c , is a mitochondrial-derived peptide, consisting of 16 residues encoded by the 12S rRNA region of the mitochondrial genome. This means that the genetic information that is translated into the peptide’s amino acid sequence has not been processed into a strip of mRNA. Rather, the peptide is translated from a strand of rRNA whose main role is not to carry genetic information but to help ribosomes work in processing such information. MOTS-cwas discovered in 2015 and has s ...

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Can Weight Loss Drugs Affect Your Fertility? A Woman’s Guide

Getting the Most Out of Weight Loss Medications: Small Changes, Big Impact

Weight Loss Without the Burnout: Creating Habits That Actually Last

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