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SARMS S4 ANDARINE SARM Andarine, more commonly known as S4 is the original SARM. Scientists discovered that while this molecule is not shaped like a steroid it does activate androgen receptors selectively in the body, favouring those in skeletal muscle, bone, and connective tissue over those in the scalp and prostate. This led to an explosion of research into molecules that selectively activate the androgen receptor (AR). S4 exerts its selectivity by having a higher binding affinity to these androgen receptors. In spite of being the first SARM developed, Andarine is still considered by many researchers to be one of the best SARMs for cutting body-fat. S4 Andarine Benefits from Clinical Research S4 Andarine has displayed multiple effects in vivo, including: Effective for Cutting Body Fat Improved Bone Health Supports Prostate Health Promotes Lean Muscle Mass Potential Side Effects of Andarine S4 is the oldest and one of the most well studied SARMs but its side effects and severity are still being learned. It is reasonable to believe that some non-androgenic side effects ...
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GW 0742 – Product Information GW 0742 is a PPARUβ/δ agonist that has been dubbed a “super cardarine”. Studies have shown that GW 0742 improves blood glucose homeostasis and increases insulin sensitivity in diabetic rats. In diabetic rats fed a high fructose diet, the group that took GW 0742 had lower blood glucose compared to the control group. Because GW 0742 is a PPAR agonist, it shows potential to increase fat loss by boosting metabolism and stimulating the utilization of fat as fuel. This may increase muscle oxidative capacity, helping to burn more calories. GW 0742 vs Cardarine GW 0742 and Cardarine are PPAR (peroxisome proliferator-activated receptor) agonists. Both drugs were originally developed by GlaxoSmithKline. Animal studies have shown that both drugs can improve insulin resistance in study subjects. They are also thought to potentially stimulate fatty acid oxidation (lower fatty acid levels) in animals. However, there is one major difference between the two. GW 0742 contains two hydrogen and four fluorine atoms, while cardarine consists of one hydrogen and three fluorine atoms. That is, GW 0742 is a fluorinated analog of cardarine. ...
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STENABOLIC SR-9009 SR9009 (also known as Stenabolic) has been studied in mice and shown to increase walking speed, reduce obesity levels, and stimulate the production of mitochondria. This can improve muscle mass and metabolism. Although SR-9009 is often associated with selective androgen receptor modulators (SARMs), it works through multiple pathways. It is actually a Rev-ErbA agonist - a nuclear receptor reverse erythrocytosis oncogene product alpha agonist - found in the liver, skeletal muscle, and brain. It is best known for its role in influencing circadian rhythms. SR-9009 and Weight Loss In a study conducted by Solt et al., mice received twice-daily injections of SR-9009 or saline while being fed a high-fat diet (composed of 60% fat and 20% carbohydrates). The goal of the study was to evaluate whether SR-9009 could help reduce body weight in humans with diet-induced obesity (source) The results showed that both groups of mice lost body fat due to the stress of the twice-daily injections. However, mice treated with SR-9009 lost 60% more fat than mice treated with saline injections. In addition, mice treated with SR-9009 had significant reductions in plasma triglycerides (12%), total chole ...
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MK2866 is a great way to increase strength, power, stamina and endurance. You can expect to see increased muscle mass and strength gains, as well as improved recovery time and reduction of fatigue. Benefits of MK2866 (Ostarine): Enhanced Muscle Growth: Ostarine is celebrated for its unparalleled ability to stimulate muscle growth, making it an ideal choice for bodybuilders and fitness enthusiasts looking to pack on lean muscle mass. Strength Enhancement: This compound not only promotes muscle growth but also enhances physical strength, allowing you to lift heavier weights and achieve greater gains. Fat Loss: Ostarine can assist in fat loss by increasing the body's metabolic rate and encouraging the use of stored fat for energy, resulting in a more defined and sculpted physique. Improved Recovery: Ostarine aids in reducing post-workout muscle soreness and accelerating recovery, ensuring less downtime between intense training sessions. Joint Health: Some users have reported potential benefits for joint health, as Ostarine may alleviate discomfort and support overall joint function. Comparison Between MK2866 (Ostarine) and Other Compounds: When comparing MK-2866 (Ostarine) with other compounds, it stand ...
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STL SARM CARDARINE STL SARM Cardarine, also known as GW501516 or Endurobol, is a PPAR (peroxisome proliferator-activated receptor) agonist and ligand-activated transcription factor that binds to receptors in skeletal muscle tissue and body fat and pushes skeletal muscle cells towards preferential lipid utilization and fat burning. PPAR is also involved in inflammation, glucose homeostasis, as well as cell proliferation, differentiation, and apoptosis, suggesting potential anti-aging effects of PPAR agonists. PPAR are located in greatest concentration in tissues with high metabolic rates like skeletal muscle, intestine, liver, heart, and kidney. GW-501516 is often wrongly classified as a selective androgen receptor modulator (SARM). As a PPAR, it shares certain commonalities with SARMs but differs from them in a few important ways. GW 501516 does not affect androgen receptors or alter testosterone levels however it does have a key involvement in energy metabolism. Cardarine Benefits from Clinical Research Increases fatty acid oxidation and promotes fat loss Lower LDL cholesterol (“bad cholesterol”) Higher HDL cholest ...
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SARMS RAD 140 SARMs RAD 140, also known as Testolone, is one of several selective androgen receptor modulators (SARMs) that was initially developed as a potential alternative to testosterone replacement therapy. It should not be confused with it’s esterified form, RAD 150, also known as TLB 150. RAD 140 binds to the androgen receptors (AR) in a selective manner and does not produce the full range of androgenic effects as similar substances like testosterone, DHT, or anabolic steroids. RAD 140 Benefits from Clinical Research Muscle Growth: A study on young male cynomolgus monkeys investigated the anabolic effects of 28 days of RAD140 at a dosage of 0.01mg/kg, 0.1mg/kg, and 1mg/kg per day. A mean weight gain of 10% was observed in both the 0.1mg/kg/day group and the 1mg/kg/day group, indicating a quantity response curve that leveled off and provided no additional benefit with higher quantities. There was no consistent effect on body fat mass in either group, however muscle mass increased in the 0.1 and 1mg/kg/day groups. No significant increases in liver enzymes or prostate weight were reported in either group suggesting a high level of selectivity for androgen receptors in muscle tissue. ...
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SARMS LGD 4033 The SARM LGD-4033, also known as Ligandrol, is a third generation nonsteroidal oral SARM with a high affinity for androgen receptors (Ki of approximately 1 nM). It is the second most popular SARM currently on the market. Unlike testosterone, which exerts its anabolic effects through the same pathway, LGD-4033 is highly selective for receptors in skeletal muscle, bone, and connective tissue, with minimal affinity for receptors in the prostate, scalp, and skin. It was developed by Ligand Pharmaceuticals to treat conditions such as muscular dystrophy and osteoporosis without the masculinizing side effects of anabolic steroids. Many researchers consider LGD 4033 to be the best SARM for producing lean mass. Sports Technology Labs is the best place to buy LGD-4033 online. LGD 4033 Benefits Clinical Studies Muscle Mass Preclinical primate data showed significant increases in lean body mass in male and female monkeys at doses of 0.6, 3, 15, or 75 mg/kg body weight over 13 weeks. In addition, 70% of the weight gain was retained after a 4-week recovery period. Only the 75 mg/kg group was discontinued after 48 days due to toxicity. This amount is significantly higher than the hig ...
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Muscle Growth What really makes YK-11 unique is that a key component of its anabolic activity is mediated through the expression of follistatin. They discovered this by co-administering an anti-follistatin antibody with YK 11 to measure the difference in effect. Follistatin has been shown to facilitate insulin-stimulated glucose and amino acid uptake into skeletal muscle cells, directly improving insulin sensitivity and increasing skeletal muscle mass. Follistatin protein also blocks inhibitory ligand binding to transforming growth factor-β. Effects of Follistatin on Muscle Tissue Perhaps the most intriguing effect of follistatin is binding and neutralizing the catabolic proteins Activin A, Activin B, and myostatin. Unfortunately, follistatin protein itself is rapidly hydrolyzed, and even when injected directly into atrophic muscle, its bioavailability and half-life are limited. However, YK-11 stimulates the body to produce more follistatin protein both systemically and locally, which may compensate for the lack of direct follistatin administration and promote muscle growth. Muscle Atrophy Animal studies investigated the effects of YK 11 as a potential treatment for sepsis-induced m ...
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Description MK677 25 mg per mL 30 mL MK677, also known as Ibutamoren, is an oral growth hormone secretagogue that mimics the effects of ghrelin. It has been studied for its potential to increase levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) in the body. Usage Muscle Growth and Strength: MK677 has become popular in the bodybuilding community for its potential to increase muscle growth and strength. Anti-Aging and Bone Density: It may help increase bone density and is considered to have anti-aging potential. Appetite Stimulation: Ibutamoren can stimulate appetite, which may be beneficial for people who want to increase calorie intake. Research Purpose: It is being studied extensively for a variety of potential therapeutic applications, including the treatment of growth hormone deficiency. Potential Effects Increases Growth Hormone Levels: By mimicking ghrelin, MK677 signals the pituitary gland to secrete growth hormone. Muscle Growth and Recovery: Helps with muscle growth and faster recovery from injuries. Fat Loss: Some evidence suggests that it helps reduce body fat. Conclusion MK677 offers interesting possibilities for muscl ...
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What is Tirzepatide? Tirzepatide is a synthetic peptide that acts as a dual agonist at the glucose-dependent insulin secretagogue polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. The compound has been studied for its potential to affect glucose regulation and energy balance. Researchers are particularly interested in Tirzepatide because of its potential role in treating metabolic disorders, including those associated with insulin resistance and excess weight. How does Tirzepatide work? Tirzepatide is designed to activate both GIP and GLP-1 receptors, which are involved in regulating insulin secretion and glucose homeostasis. By stimulating these receptors, Tirzepatide can enhance insulin secretion in response to elevated blood glucose, inhibit glucagon release, and slow gastric emptying. In addition, this dual agonist effect may help reduce appetite and caloric intake by acting on receptors within the central nervous system, which may be beneficial for weight management. What are the potential benefits of Tirzepatide? Research suggests that Tirzepatide may offer several potential benefits: Improved blood sugar control: Tirzepat ...
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Structure Sequence: Glu-Ala-Lys-Ser-GIn-Gly-Gly-Ser-Asn Molecular formula: C 33 H 54 N 12 O 15 Peptide purity: greater than 98% Additional details: TFA-free, mannitol-free Storage: This product must be stored at 4°C. Not suitable for freezing. Zinc-thymol is for external use only Description Hair loss occurs in a large proportion of the adult population and increases with age. Both men and women can experience hair loss, but it is more common in men. In the West, an estimated 50% of men will experience noticeable hair loss before the age of 50. The most common form of hair loss in men is androgenic alopecia (male pattern baldness). Most hair loss is due to follicular inactivation, which means that the follicles stop growing hair. Literature also suggests that with aging, the fat layer of the scalp thins, leading to the inactivation of stem cells that regulate hair growth, which can lead to hair loss. Zinc deficiency can also lead to hair loss. Thymosin is a nonapeptide from the thymus gland. Zinc and thymosin are two natural compounds involved in hair follicle growth that have been found to promote hair growth. Early reports of thymus extracts ...
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What is Thymosin Alpha 1? Thymosin Alpha 1, also known as TA1, is a 28 amino acid peptide. It is naturally produced and isolated from the human thymus, a small gland that makes and trains immune cells (T-cells). The T-cells help your immune system fight disease and infection. Thymosin Alpha 1 was first isolated from the calf thymus in 1977. Since then, two additional methods have been developed to extract this peptide from its source. These include solid-state synthesis (the popular method) and genetic engineering processes. Like the source (thymus) from which it is isolated, TA1 possesses the ability to enhance, restore and modify your immune response. It has also shown promise in various clinical applications, including viral, fungal, and bacterial infectious diseases and cancer. Recent research has indicated that TA1 might be used for the treatment of severe sepsis. The peptide has also been reported to prevent invasive infections in bone-marrow transplanted patients. In clinical studies, it has displayed promise as a vaccine adjuvant. How does Thymosin Alpha 1 Work? Thymosin Alpha 1 has a dual mechanism of action: Immune Modulating Effect 】 Thymosin Alpha 1 exe ...
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What is Tesamorelin? Tesamorelin is a stabilized synthetic analogue of Growth Hormone Releasing Hormone (GHRH),not specifically from the hypothalamus, used for the reduction of excess abdominal fat in HIV-patients with lipodystrophy. Lipodystrophy is a metabolic condition often associated with insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for the treatment of HIV infection. Mechanism of Action Tesamorelin works by mimicking the natural Growth Hormone Releasing Hormone, stimulating the pituitary gland to release more growth hormone. This increase in growth hormone leads to various metabolic effects, majorly the reduction of excess abdominal fat, and helps improve body composition. By binding to GHRH, Tesamorelin causes a series of physiological reactions that result in a reduction of visceral fat in the abdominal area. Potential Benefits of Tesamorelin The following are the benefits of Tesamorelin: Fat loss and improvement in body composition: One of the well-known benefits of tesamorelin is the visceral fat reduction. Research shows that tesamorelin may help in the reduction of excess abdominal fat and also help improve the body composit ...
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What is TB-500? TB-500 is a 43 amino acid synthetic analog of thymosin B-4 (TB-4), which occurs naturally in nearly all mammalian cells. TB-500 is known for its effects on actin, cell migration, and wound healing. Animal models and in vitro studies have shown that TB-500 can improve blood vessel growth, accelerate wound healing, reduce inflammation, and promote production of extracellular matrix. The peptide is currently being studied for its ability to reduce oxidative stress in spinal cord injuries, improve recovery after heart attacks, and have a variety of anti-aging effects. TB-500 Mechanism of Action TB-500 is the active domain of TB-4 and primarily acts as an actin-binding protein. Actin is an important component of cellular structure and makes up microfilaments. Microfilaments are responsible for giving cells their shape, protecting the integrity of cell membranes, allowing cells to move/migrate, and certain steps in cell reproduction. Actin is also one of the main components of muscle protein. Without actin, muscles cannot contract. Actin-binding proteins such as TB-4 sequester actin monomers (single units of actin), thereby protecting them from degradation and allowing them to polymerize into microfilaments ...
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What is Survodutide? Survodutide 10MG is a research compound studied for potential benefits in obesity and glucose management. Similar to Mazdutide and Retatrutide, Survodutide shows high efficacy. Researchers hypothesize that, when combined with proper diet and exercise, it might significantly enhance obesity reduction. Additionally, studies explore its effects on metabolic regulation and cardiovascular health. How Does Survodutide Work? Survodutide stands out in obesity research due to its multifaceted mechanisms of action: Multi-Receptor Agonist: Survodutide targets multiple receptors involved in regulating metabolism. This action slows gastric emptying, reduces postprandial glucose levels, and promotes satiety. Consequently, it leads to decreased food intake and improved energy balance. Enhancing Satiety: By acting on the brain’s satiety centers, Survodutide helps reduce appetite and prolong feelings of fullness. This reduction in caloric intake supports efforts in obesity reduction. Glucose Optimization: Survodutide aids in better glucose regulation by slowing gastric emptying and modulating insulin and glucagon release. This dual action results in improved glycemic control, b ...
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Key Features: Wrinkle Reduction: Effectively reduces expression lines and wrinkles. Botulinum Toxin Alternative: Provides a safer, non-invasive alternative to traditional botulinum toxin treatments. Skin Smoothness: Improves skin texture and smoothness. Anti-Aging: Reduces signs of aging and maintains a youthful appearance. Research Support: Studies have shown it to be effective in reducing the depth and formation of wrinkles. Description SNAP-8 is a naturally derived, non-toxic, non-invasive peptide that has been shown to have the potential to reduce facial wrinkles and improve skin appearance. It is an extension of the hexapeptide ARGIRELINE, known for its ability to modulate muscle contraction, thereby reducing the formation of fine lines and wrinkles. Structure and Modifications SNAP-8 is an octapeptide composed of glutamyl and heptapeptide amino acids. Its structure allows it to mimic the N-terminus of SNAP-25, a protein involved in the SNARE complex, which is essential for neurotransmitter release and muscle contraction. Synthesis and Studies SNAP-8 has been synthesized using a variety of methods, including solid phase synthesis. Studies have shown that it is ...
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What is Sermorelin? Sermorelin is a synthetic peptide analog of human growth hormone-releasing hormone (GHRH). It was developed by EMD Serono, a German company, for the treatment of growth hormone deficiency (GHD) in children and adults. The main function of the peptide is to stimulate the body to produce and release growth hormone (GH). After clinical trials, growth hormone-releasing peptide was first approved by the U.S. Food and Drug Administration (FDA) in 1997 under the trade name "Geref" for the treatment of growth hormone deficiency (GHD) in children and adults. In 2008, the FDA stopped approving the drug for commercial reasons unrelated to safety or effectiveness. Growth hormone-releasing peptide can also be used as a diagnostic agent to evaluate whether the pituitary gland in a particular patient is functioning properly and releasing adequate amounts of growth hormone. Other applications of this peptide are currently being studied, including its role in the diagnosis and treatment of hormone deficiencies, including its role in sleep quality, heart health, and even as a new type of brain tumor treatment. Sermorelin Benefits | Clinical Trials Our team conducted a literature review u ...
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Class of Compound: Peptide Mechanism of Action: Semax is known to stimulate neurotrophic factors in the central nervous system, namely Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF). It further appears to impact serotonin, dopamine, and enkephalin signaling. Notable Studies: · Semax in the treatment of glaucomatous optic neuropathy in patients with normalized ophthalmic tone · The efficacy of semax in the treatment of patients at different stages of ischemic stroke · Synthetic ACTH analog Semax displays nootropic‐like activity in humans What is Semax? Semax is a synthetic peptide that was first developed by Russian researchers in the 1980s. It is authorized in Russia and Ukraine for indications including ischemic brain stroke, encephalopathy, optic nerve atrophy, and cognitive disorders such as dementia. Research suggests that Semax may offer potential benefits to patients suffering from a variety of neurological conditions, including Alzheimer's, traumatic brain injury (TBI), and stroke. Semax is an ana ...
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What Is Compounded Semaglutide? Compounded semaglutide is a form of the diabetes medication semaglutide that is custom-prepared by compounding pharmacies. This service has become especially important due to frequent shortages of GLP-1 medications, including well-known brands like Wegovy, Ozempic, and Rybelsus. Such shortages are often caused by manufacturing delays, rising demand and disruptions in the supply chain, leaving many patients without essential treatment. Compounded semaglutide offers a reliable alternative when these name-brand medications are not available. With state-of-the-art 503A and 503B facilities, Olympia Pharmaceuticals can tailor patient-specific prescriptions and office-use preparations of GLP-1 medications. Our adherence to stringent national and state regulations ensures that healthcare providers and their patients can maintain uninterrupted treatment. What Is Compounded Semaglutide Prescribed For? Semaglutide is primarily prescribed for adults with type 2 diabetes to improve blood glucose control. Additionally, it may be used for weight management in individuals who are either overweight or obese and have at least one weight-related condition, such as hypertension or dyslipi ...
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Class of Compound: Peptide Mechanism of Action: Selank acts on the central nervous system by influencing the levels and activity of neurotransmitters like serotonin, dopamine, and GABA, which can result in anxiolytic effects, mood improvement, and cognitive enhancement. The peptide also interacts with the immune system by influencing gene expression and modulating cytokine balance. Notable Studies: · Semax and Selank inhibit the enkephalin-degrading enzymes from human serum · Selank administration affects the expression of some genes involved in GABAergic neurotransmission · Immunomodulatory effects of Selank in patients with anxiety-asthenic disorders What is Selank? Selank is a synthetic analog of tuftsin, an endogenous tetrapeptide that plays a role in regulating the immune system. Some researchers informally classify Selank as a nootropic—a compound that can enhance cognitive function, improve memory, and increase mental clarity. Selank was developed in the early 1990s at the Russian Academy of Sciences and has primarily been studied fo ...
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How does Retatrutide work? Retatrutide may function by activating multiple receptors, including those for glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon. This multi-receptor activity could lead to enhanced insulin secretion, reduced appetite, and increased energy expenditure. The compound is being studied for its potential influence on the central nervous system, gastrointestinal tract, and peripheral tissues. and peripheral tissues. Potential Benefits of Retatrutide Studies on Retatrutide suggest that it may offer a variety of potential benefits, including: Weight Management: By potentially reducing appetite and increasing energy expenditure, Retatrutide may help manage weight. Improving Glycemic Control: The compound may enhance insulin secretion and sensitivity, helping to better regulate blood sugar. Lipid Metabolism: Retatrutide peptides can affect lipid metabolism, potentially reducing lipid levels and improving cardiovascular health markers. Broad Metabolic Effects: Due to Retatrutide's multi-receptor effects, it may offer a wide range of metabolic benefits to study sub ...
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Description PT-141, also known as bremelanotide, is an innovative new peptide hormone therapy for men and women that improves sexual function. PT-141 is an effective and highly effective treatment for erectile dysfunction and increased libido in men, and for improving sexual arousal disorders in women. PT 141 peptide gives you desire and drive while increasing blood flow to the penis or vagina and clitoris, restoring intimacy and passion to your relationship. PT 141 addresses these issues and helps resolve sexual difficulties. PT-141 works directly through the nervous system to increase arousal, desire, and sexual satisfaction. Drugs such as Viagra and Cialis work through the vascular system and only give you an erection. However, PT-141 not only gives you an erection, it also gives you desire and drive, restoring intimacy and passion to your relationship. Benefits of PT 141 PT 141 works by stimulating melanocortin receptors in the brain. It can be injected subcutaneously or inhaled through the nose to treat sexual dysfunction. It is known to work quickly, usually in less than an hour. This peptide can offer many benefits to men and women with decreased libido and sexual performance. Trea ...
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What is PEG-MGF peptide? PEG MGF, short for PEGylated mechano-growth factor, is a two-component anabolic peptide. PEG MGF is a well-known derivative of the compound insulin-like growth factor-1 (IGF-1). IGF-1 is thought to play an important role in the regulation of growth hormone (GH). In addition, this chemical may also help promote bone and tissue growth. PEG MGF promotes muscle growth by prompting various receptors to drive myoblasts to divide. Several studies have also shown that PEG MGF can increase the number of muscle stem cells that bind to existing muscle cells, thereby promoting muscle growth. PEG MGF has a short half-life of about 5 to 7 minutes. To address this, this experimental chemical is PEGylated. PEGylation is performed by adding polyethylene glycol (PEG) to the peptide. By adding the PEG group, the half-life of MGF can be safely and effectively extended to 48-72 hours. Possible Applications of PEGylated Mechano-Growth Factor Peptides: PEG MGF Peptides and Bone Repair In the animal model mouse, MGF treatment improved the migration of chondrocytes (cells responsible for cartilage formation) from the bone to the cartilage where they are needed. PEGylated Me ...
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What is oxytocin? The peptide hormone is made up of 9 amino acids. It is produced in the hypothalamus, an area of the brain that controls heart rate, blood pressure, and digestion. OT is released into the bloodstream by the posterior pituitary gland. Oxytocin was discovered by Sir Henry Dale in 1996. He found that extracts from the posterior pituitary gland of humans caused the uterus of pregnant cats to contract. Sir Henry Dale also coined the name oxytocin, which means "quick labor" in Greek. This peptide hormone controls many functions. It has an impact on labor, milk secretion during breastfeeding, and bonding with newborns in humans. It also plays an important role in sexual arousal, romantic attachment, and other social interactions. It is also known as the "love hormone." A 2012 study found that levels of this hormone were significantly higher in newly-in-love people than in singles. The findings suggest that it may play an important role in the initial stages of a relationship. Pure Rawz sells this product for research use only. How does oxytocin work? Research suggests that it interacts with neural pathways responsible for processing motivation-related stimuli. In particular, ...
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