GW0742

POWDER

Because GW 0742 is a PPAR agonist, it shows potential to increase fat loss by boosting metabolism and stimulating the utilization of fat as fuel.
This may increase muscle oxidative capacity, helping to burn more calories.

12345@Ursofik.com

Inquire Now

Description

GW 0742 – Product Information

GW 0742 is a PPARUβ/δ agonist that has been dubbed a “super cardarine”.

Studies have shown that GW 0742 improves blood glucose homeostasis and increases insulin sensitivity in diabetic rats. In diabetic rats fed a high fructose diet, the group that took GW 0742 had lower blood glucose compared to the control group.

Because GW 0742 is a PPAR agonist, it shows potential to increase fat loss by boosting metabolism and stimulating the utilization of fat as fuel.

This may increase muscle oxidative capacity, helping to burn more calories.

GW 0742 vs Cardarine

GW 0742 and Cardarine are PPAR (peroxisome proliferator-activated receptor) agonists.

Both drugs were originally developed by GlaxoSmithKline. Animal studies have shown that both drugs can improve insulin resistance in study subjects. They are also thought to potentially stimulate fatty acid oxidation (lower fatty acid levels) in animals.

However, there is one major difference between the two. GW 0742 contains two hydrogen and four fluorine atoms, while cardarine consists of one hydrogen and three fluorine atoms. That is, GW 0742 is a fluorinated analog of cardarine.

PureRawz sells GW 0742 and Cardarine for laboratory research.

GW 0742 and Metabolism

A study was conducted to investigate whether PPARβ/δ agonist treatment would improve exercise-induced immunometabolic changes in diet-induced obese mice. Results showed increased fatty acid oxidation gene expression and AMPK activity.

These effects were associated with decreased visceral adipose tissue mass (burning fat) and decreased skeletal muscle inflammation, as well as increased skeletal muscle oxidative capacity and insulin sensitivity.

GW 0742 and Insulin Resistance

Insulin resistance is an abnormal condition in which cells do not respond normally to insulin. Insulin resistance leads to increased insulin secretion in the body, which in turn leads to high blood pressure, atherosclerosis (hardening of the arteries), and increased triglyceride levels.

GW 0742 has been shown to improve metabolic abnormalities, including insulin resistance in skeletal muscle of mice fed a high fructose corn syrup diet. However, the effects of GW 0742 on systemic insulin sensitivity remain unexplained.

GW 0742 and inflammation

A study investigated the effects of GW 0742 on inflammation. The study found that the PPAR agonist reduced many parameters of inflammation and apoptosis (cell death). Overall, the results showed that GW 0742 reduced lung inflammation induced by bleomycin instillation in mice.

GW 0742 and diabetes

Animal experimental data showed that GW 0742 was able to improve glucose homeostasis (glucose uptake) in diabetic rats by activating PPAR-δ. Therefore, PPAR-δ is a good target for future development of anti-diabetic drugs.

GW 0742 and hypertension

A 2011 study aimed to investigate whether GW 0742 might exert antihypertensive effects in spontaneously hypertensive rats (SHR). GW 0742 induced a gradual decrease in systolic blood pressure and heart rate in SHR. Based on the results, the researchers proposed PPARβ as a new therapeutic target for hypertension.

Summary

GW 0742 is a PPAR receptor agonist that has demonstrated the potential to reduce inflammation, improve hypertension, and improve metabolic abnormalities in mice. However, due to the lack of human studies, its effects need further investigation.

We have cooperated with experienced shipping forwarders for many years, they arrange the shipment. No matter by express, by air or by sea, we will track the course of the goods all the way, to make sure goods arrive at you on time and in good condition.

Previous
S4

Next
SR9009

GET A QUOTE

Whether you have any questions about our products, please feel free to contact us, we will reply as soon as possible.

Melanotan 2

Mechanism of Action: Melanotan II is an agonist of melanocortin receptors 1 and 4 (MC-1R and MC-4R), which respectively regulate melanin production and male erectile function. It is also believed to stimulate MC-3R, which affects appetite and energy levels. Notable Studies: · Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study · Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan 2 · An unhealthy glow? A review of Melanotan use and associated clinical outcomes What is Melanotan 2? Melanotan 2 is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH). The molecule was first developed in the 1980s by University of Arizona researchers, who were looking to clarify the nature and role of the melanocortin receptors in physiological functions. Namely, the peptide was intended to be used as a sunless tanning agent, but was subsequently found to strongly affect sexual function and appetite . Melanotan 2 (MT-II) should not be confused with another ...

TB-500

What is TB-500? TB-500 is a 43 amino acid synthetic analog of thymosin B-4 (TB-4), which occurs naturally in nearly all mammalian cells. TB-500 is known for its effects on actin, cell migration, and wound healing. Animal models and in vitro studies have shown that TB-500 can improve blood vessel growth, accelerate wound healing, reduce inflammation, and promote production of extracellular matrix. The peptide is currently being studied for its ability to reduce oxidative stress in spinal cord injuries, improve recovery after heart attacks, and have a variety of anti-aging effects. TB-500 Mechanism of Action TB-500 is the active domain of TB-4 and primarily acts as an actin-binding protein. Actin is an important component of cellular structure and makes up microfilaments. Microfilaments are responsible for giving cells their shape, protecting the integrity of cell membranes, allowing cells to move/migrate, and certain steps in cell reproduction. Actin is also one of the main components of muscle protein. Without actin, muscles cannot contract. Actin-binding proteins such as TB-4 sequester actin monomers (single units of actin), thereby protecting them from degradation and allowing them to polymerize into microfi ...

OXYTOCIN

What is oxytocin? The peptide hormone is made up of 9 amino acids. It is produced in the hypothalamus, an area of the brain that controls heart rate, blood pressure, and digestion. OT is released into the bloodstream by the posterior pituitary gland. Oxytocin was discovered by Sir Henry Dale in 1996. He found that extracts from the posterior pituitary gland of humans caused the uterus of pregnant cats to contract. Sir Henry Dale also coined the name oxytocin, which means "quick labor" in Greek. This peptide hormone controls many functions. It has an impact on labor, milk secretion during breastfeeding, and bonding with newborns in humans. It also plays an important role in sexual arousal, romantic attachment, and other social interactions. It is also known as the "love hormone." A 2012 study found that levels of this hormone were significantly higher in newly-in-love people than in singles. The findings suggest that it may play an important role in the initial stages of a relationship. Pure Rawz sells this product for research use only. How does oxytocin work? Research suggests that it interacts with neural pathways responsible for processing motivation-related stimuli. In particular, ...

IPAMORELIN

Compound Class: Peptide Mechanism of Action: Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist that triggers and stimulates growth hormone production by mimicking ghrelin. It binds to ghrelin receptors, stimulating growth hormone release, and inhibits somatostatin and suppresses its effects. Notable Studies: · Ipamorelin, the first selective growth hormone secretagogue · The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced reductions in bone formation in adult rats · The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats What is ipamorelin? Ipamorelin is a laboratory-made compound known as growth hormone-releasing peptide. It stimulates the body to release growth hormone, which promotes systemic growth of muscle, bone, vascular system, and other cells and body tissues. Ipamorelin is unique among growth hormone-releasing peptides in that, unlike most growth hormone-releasing peptides, it does not activate the body's natural stress response. This gives ipamorelin an advantage over similar compounds. However, researc ...

MOTS-C

Class of Compound: Peptide Mechanism of Action: While the precise mechanism of action of MOTS-c is currently under investigation, it is hypothesized that its metabolic effects are mediated through its translocation to the nucleus and subsequent activation of AMPK. Notable Studies: · MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. · The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. · MOTS-c Functionally Prevents Metabolic Disorders. Metabolites. What is MOTS-c? MOTS-c , is a mitochondrial-derived peptide, consisting of 16 residues encoded by the 12S rRNA region of the mitochondrial genome. This means that the genetic information that is translated into the peptide’s amino acid sequence has not been processed into a strip of mRNA. Rather, the peptide is translated from a strand of rRNA whose main role is not to carry genetic information but to help ribosomes work in processing such information. MOTS-cwas discovered in 2015 and has s ...

We Provide Best Services
Agent

Email For Us

Call For Us

GW0742

12345@Ursofik.com

Previous
S4

Next
SR9009

GET A QUOTE

Categories

Hot products

Melanotan 2

TB-500

OXYTOCIN

IPAMORELIN

MOTS-C

New Products

Follow Us

Useful Link

Products

Newsletter

Contact Us

GW0742

S4

SR9009

GET A QUOTE

Related products

Categories

Hot products

New Products

Useful Link

Products

Contact Us

GET IN TOUCH!