IGF-1 LR3

PEPTIDES

IGF-1, or insulin-like growth factor, is a potent growth factor found in mammalian blood. This peptide manages and regulates growth hormone (GH) levels. IGF-1 LR3 is the abbreviated form of IGF-1, which some researchers consider to be the most potent growth factor.

IGF-1 LR3 is a chemically altered amino acid chain of 83 amino acids. At position 3 on the chain, Glu(E) is replaced by Arg(R), resulting in the name LR3. This substitution at position 3 prevents IGF-1 from binding to proteins, thereby extending its half-life.

12345@Ursofik.com

Inquire Now

Description

What is IGF-1 LR3?

Possible Applications of IGF-1 LR3

Insulin-like growth factors have been extensively studied and tested clinically. Below we will highlight some potential future research implications of IGF-1 LR3, known as IGF-binding protein.

Possible Promotion of Cell Division

Like IGF-1, IGF-1 LR3 is a potential potent stimulator of cell proliferation and division. Its main potential effects are thought to be on connective tissues such as muscle and bone. But it may also promote cell division in kidney, liver, skin, nerve, lung, and blood tissue.
Of note, studies have shown that IGF-1 LR3 and all IGF-1 derivatives do not promote cell enlargement, but rather promote cell division and proliferation.

For example, in the case of muscle potential, IGF-1 LR3 may not cause muscle cell growth and enlargement, but may increase the total number of muscle cells.

This property of IGF-1 LR3 requires further study.

Potential to Promote Fat Metabolism and Fight Diabetes
IGF-1 LR3 is thought to help lower blood sugar levels. It may also indirectly promote fat metabolism by binding to insulin and IGF 1R receptors. These effects may increase glucose uptake from the blood by muscle, liver, and nerve cells.

According to a 2013 study, this may lead to an overall decrease in blood sugar levels, which in turn may trigger fat tissue and the liver to begin breaking down glycogen and triglycerides. This may result in a net decrease in fat tissue and net energy expenditure.

This makes IGF-1 LR3 a derivative of insulin-like growth factor and a potential treatment for reducing insulin requirements in patients with type 2 diabetes.

Despite these health benefits, this research chemical still needs to undergo more in-depth and large-scale clinical trials.

May Impair Myostatin
Myostatin (also known as growth differentiation factor 8) is a muscle protein that primarily inhibits the growth and differentiation of muscle cells.

In a mouse model of DMD, the study found that IGF-1 R3 and other IGF-1 derivatives were able to counteract the negative effects of myostatin, thereby protecting muscle cells and preventing apoptosis. It appears to counteract myostatin by activating a muscle protein called MyoD.

How does IGF-1 LR3 work?

Research suggests that IGF-1 LR3 works by potentially binding to cell receptors in muscle cells and activating cell communication, which may help improve muscle growth and the rate at which muscles grow.

IGF-1 LR3 may also block the entry of glucose into cells. This may aid in fat burning and the use of fat for energy.

Safety and Side Effects

Hypoglycemia was a serious and potentially fatal side effect of IGF-1 LR3 in study subjects. Hypoglycemia is a dangerously low blood sugar level that can cause shaking, sweating, dizziness, hunger, confusion, and unconsciousness.

FAQs

What is the difference between IGF-1 and IGF-1 LR3?
IGF-1 differs from IGF-1 LR3 in that the latter has arginine instead of glutamate at the third point in the amino acid sequence.

It is also more potent and lasts longer. IGF-1 LR3 peptides can also inhibit the entry of glucose into cells to promote fat burning.

Finally, IGF-1 LR3 does not stick to the IGF binding protein in a similar way to IGF-1. As a result, the modified version has been found to stay in the blood longer than IGF-1.

What is the difference between the mediator and receptor grades of IGF-1 LR3?
For IGF-1 LR3, the terms "media grade" and "receptor grade" refer to different qualities or purity of the peptide. Here is a breakdown of the differences:

Media Grade IGF-1 LR3:

Media grade IGF-1 LR3 refers to a less pure peptide that is often used in laboratory research and cell culture studies. It is primarily used as an additive in cell culture media to provide growth factors to support cell growth and proliferation. Media grade IGF-1 LR3 may contain impurities and is not suitable for human use.

Receptor Grade IGF-1 LR3: Receptor grade IGF-1 LR3, also known as pharmaceutical grade or research grade, refers to a highly pure peptide that meets strict quality standards. It is often used in research settings, preclinical studies, and sometimes clinical trials. Receptor grade IGF-1 LR3 undergoes a more rigorous purification process to remove impurities and ensure higher quality and consistency.

What is the half-life of IGF-1 LR3?

Research shows that IGF-1 has a very short half-life, so it is destroyed very quickly. This is the main reason why IGF-1 was engineered to produce an amino acid analog with a longer half-life, IGF-1 LR3.

The half-life of IGF-1 LR3 is approximately 20 – 30 hours.

We have cooperated with experienced shipping forwarders for many years, they arrange the shipment. No matter by express, by air or by sea, we will track the course of the goods all the way, to make sure goods arrive at you on time and in good condition.

Previous
KISSPEPTIN

Next
HMG

GET A QUOTE

Whether you have any questions about our products, please feel free to contact us, we will reply as soon as possible.

Melanotan 2

Mechanism of Action: Melanotan II is an agonist of melanocortin receptors 1 and 4 (MC-1R and MC-4R), which respectively regulate melanin production and male erectile function. It is also believed to stimulate MC-3R, which affects appetite and energy levels. Notable Studies: · Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study · Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan 2 · An unhealthy glow? A review of Melanotan use and associated clinical outcomes What is Melanotan 2? Melanotan 2 is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH). The molecule was first developed in the 1980s by University of Arizona researchers, who were looking to clarify the nature and role of the melanocortin receptors in physiological functions. Namely, the peptide was intended to be used as a sunless tanning agent, but was subsequently found to strongly affect sexual function and appetite . Melanotan 2 (MT-II) should not be confused with another ...

TB-500

What is TB-500? TB-500 is a 43 amino acid synthetic analog of thymosin B-4 (TB-4), which occurs naturally in nearly all mammalian cells. TB-500 is known for its effects on actin, cell migration, and wound healing. Animal models and in vitro studies have shown that TB-500 can improve blood vessel growth, accelerate wound healing, reduce inflammation, and promote production of extracellular matrix. The peptide is currently being studied for its ability to reduce oxidative stress in spinal cord injuries, improve recovery after heart attacks, and have a variety of anti-aging effects. TB-500 Mechanism of Action TB-500 is the active domain of TB-4 and primarily acts as an actin-binding protein. Actin is an important component of cellular structure and makes up microfilaments. Microfilaments are responsible for giving cells their shape, protecting the integrity of cell membranes, allowing cells to move/migrate, and certain steps in cell reproduction. Actin is also one of the main components of muscle protein. Without actin, muscles cannot contract. Actin-binding proteins such as TB-4 sequester actin monomers (single units of actin), thereby protecting them from degradation and allowing them to polymerize into microfi ...

OXYTOCIN

What is oxytocin? The peptide hormone is made up of 9 amino acids. It is produced in the hypothalamus, an area of the brain that controls heart rate, blood pressure, and digestion. OT is released into the bloodstream by the posterior pituitary gland. Oxytocin was discovered by Sir Henry Dale in 1996. He found that extracts from the posterior pituitary gland of humans caused the uterus of pregnant cats to contract. Sir Henry Dale also coined the name oxytocin, which means "quick labor" in Greek. This peptide hormone controls many functions. It has an impact on labor, milk secretion during breastfeeding, and bonding with newborns in humans. It also plays an important role in sexual arousal, romantic attachment, and other social interactions. It is also known as the "love hormone." A 2012 study found that levels of this hormone were significantly higher in newly-in-love people than in singles. The findings suggest that it may play an important role in the initial stages of a relationship. Pure Rawz sells this product for research use only. How does oxytocin work? Research suggests that it interacts with neural pathways responsible for processing motivation-related stimuli. In particular, ...

IPAMORELIN

Compound Class: Peptide Mechanism of Action: Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist that triggers and stimulates growth hormone production by mimicking ghrelin. It binds to ghrelin receptors, stimulating growth hormone release, and inhibits somatostatin and suppresses its effects. Notable Studies: · Ipamorelin, the first selective growth hormone secretagogue · The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced reductions in bone formation in adult rats · The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats What is ipamorelin? Ipamorelin is a laboratory-made compound known as growth hormone-releasing peptide. It stimulates the body to release growth hormone, which promotes systemic growth of muscle, bone, vascular system, and other cells and body tissues. Ipamorelin is unique among growth hormone-releasing peptides in that, unlike most growth hormone-releasing peptides, it does not activate the body's natural stress response. This gives ipamorelin an advantage over similar compounds. However, researc ...

MOTS-C

Class of Compound: Peptide Mechanism of Action: While the precise mechanism of action of MOTS-c is currently under investigation, it is hypothesized that its metabolic effects are mediated through its translocation to the nucleus and subsequent activation of AMPK. Notable Studies: · MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. · The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. · MOTS-c Functionally Prevents Metabolic Disorders. Metabolites. What is MOTS-c? MOTS-c , is a mitochondrial-derived peptide, consisting of 16 residues encoded by the 12S rRNA region of the mitochondrial genome. This means that the genetic information that is translated into the peptide’s amino acid sequence has not been processed into a strip of mRNA. Rather, the peptide is translated from a strand of rRNA whose main role is not to carry genetic information but to help ribosomes work in processing such information. MOTS-cwas discovered in 2015 and has s ...

We Provide Best Services
Agent

Email For Us

Call For Us

IGF-1 LR3

12345@Ursofik.com

Previous
KISSPEPTIN

Next
HMG

GET A QUOTE

Categories

Hot products

Melanotan 2

TB-500

OXYTOCIN

IPAMORELIN

MOTS-C

New Products

Follow Us

Useful Link

Products

Newsletter

Contact Us

IGF-1 LR3

KISSPEPTIN

HMG

GET A QUOTE

Related products

Categories

Hot products

New Products

Useful Link

Products

Contact Us

GET IN TOUCH!