STL SARM CARDARINE

STL SARM Cardarine, also known as GW501516 or Endurobol, is a PPAR (peroxisome proliferator-activated receptor) agonist and ligand-activated transcription factor that binds to receptors in skeletal muscle tissue and body fat and pushes skeletal muscle cells towards preferential lipid utilization and fat burning. PPAR is also involved in inflammation, glucose homeostasis, as well as cell proliferation, differentiation, and apoptosis, suggesting potential anti-aging effects of PPAR agonists.

PPAR are located in greatest concentration in tissues with high metabolic rates like skeletal muscle, intestine, liver, heart, and kidney. GW-501516 is often wrongly classified as a selective androgen receptor modulator (SARM). As a PPAR, it shares certain commonalities with SARMs but differs from them in a few important ways. GW 501516 does not affect androgen receptors or alter testosterone levels however it does have a key involvement in energy metabolism.

Cardarine Benefits from Clinical Research

• Increases fatty acid oxidation and promotes fat loss
• Lower LDL cholesterol (“bad cholesterol”)
• Higher HDL cholesterol (“good cholesterol”)
• Increases endurance
• Reduces inflammation
• Decreases insulin resistance and improves glucose tolerance
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Side Effects of SARM Cardarine

While Cardarine is not known to cause androgenic side effects like anabolic androgenic steroids, data in rats indicates that doses of 3mg/kg/day (180-240mg per day in the average 60-80kg adult), significantly higher than those used in mammalian trails, caused cancer to develop quickly in several organs. Anecdotal data online indicates little in the way of noticeable side effects but more research is necessary to determine the overall safety profile of GW501516 before it can be approved for human use by the FDA.