中文版 
Spain 
Arabic
Russian
Korean
Thai
vietnamese
Persian
Deutsch
Türkce
日本語
SARMS LGD 4033 The SARM LGD-4033, also known as Ligandrol, is a third generation nonsteroidal oral SARM with a high affinity for androgen receptors (Ki of approximately 1 nM). It is the second most popular SARM currently on the market. Unlike testosterone, which exerts its anabolic effects through the same pathway, LGD-4033 is highly selective for receptors in skeletal muscle, bone, and connective tissue, with minimal affinity for receptors in the prostate, scalp, and skin. It was developed by Ligand Pharmaceuticals to treat conditions such as muscular dystrophy and osteoporosis without the masculinizing side effects of anabolic steroids. Many researchers consider LGD 4033 to be the best SARM for producing lean mass. Sports Technology Labs is the best place to buy LGD-4033 online. LGD 4033 Benefits Clinical Studies Muscle Mass Preclinical primate data showed significant increases in lean body mass in male and female monkeys at doses of 0.6, 3, 15, or 75 mg/kg body weight over 13 weeks. In addition, 70% of the weight gain was retained after a 4-week recovery period. Only the 75 mg/kg group was discontinued after 48 days due to toxicity. This amount is significantly higher than the highest amo ...
Read More
Muscle Growth What really makes YK-11 unique is that a key component of its anabolic activity is mediated through the expression of follistatin. They discovered this by co-administering an anti-follistatin antibody with YK 11 to measure the difference in effect. Follistatin has been shown to facilitate insulin-stimulated glucose and amino acid uptake into skeletal muscle cells, directly improving insulin sensitivity and increasing skeletal muscle mass. Follistatin protein also blocks inhibitory ligand binding to transforming growth factor-β. Effects of Follistatin on Muscle Tissue Perhaps the most intriguing effect of follistatin is binding and neutralizing the catabolic proteins Activin A, Activin B, and myostatin. Unfortunately, follistatin protein itself is rapidly hydrolyzed, and even when injected directly into atrophic muscle, its bioavailability and half-life are limited. However, YK-11 stimulates the body to produce more follistatin protein both systemically and locally, which may compensate for the lack of direct follistatin administration and promote muscle growth. Muscle Atrophy Animal studies investigated the effects of YK 11 as a potential treatment for sepsis-induced muscle at ...
Read More
Description MK677, also known as Ibutamoren, is an oral growth hormone secretagogue that mimics the effects of ghrelin. It has been studied for its potential to increase levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) in the body. Usage Muscle Growth and Strength: MK677 has become popular in the bodybuilding community for its potential to increase muscle growth and strength. Anti-Aging and Bone Density: It may help increase bone density and is considered to have anti-aging potential. Appetite Stimulation: Ibutamoren can stimulate appetite, which may be beneficial for people who want to increase calorie intake. Research Purpose: It is being studied extensively for a variety of potential therapeutic applications, including the treatment of growth hormone deficiency. Potential Effects Increases Growth Hormone Levels: By mimicking ghrelin, MK677 signals the pituitary gland to secrete growth hormone. Muscle Growth and Recovery: Helps with muscle growth and faster recovery from injuries. Fat Loss: Some evidence suggests that it helps reduce body fat. Conclusion MK677 offers interesting possibilities for muscle growth and GH stimulation, but should be used with cauti ...
Read More
Metformin The medical term for metformin is biguanide. Brand names include: Glucophage; Glucophage XR; Diaformin; Diabex; Fortamet; Glumetza; Riomet. Metformin is the number one drug of choice by doctors to commence on when diagnosed with type 2 diabetes. Why is this? Working to improve the ways our natural insulin works in our body and helping to regulate blood sugars by its action on the liver, metformin also has been associated with no hypoglycaemia (low blood sugars); no weight gain (and some studies even suggest weight loss) and is generally well tolerated. It is one of the most affordable diabetes medications available and is increasingly being researched as it seems to have a number of other beneficial effects, playing a role in heart health, stroke prevention, cancer and general anti-ageing ( Benefits of Metformin - read more below). Originally deriving from a plant, the French lilac, metformin has been around for a very long time, centuries in fact, and in its current tablet form since the 1970’s. Introducing changes to your diet and exercise in combination with metformin have the biggest benefits in regulating blood sugars. Sometimes Metformin is started in pre-d ...
Read More
NAD+ Research A large number of animal and human studies have been conducted on the potential applications of NAD+. Here are some relevant findings: NAD+ Anti-Aging Many people are looking for anti-aging secrets, and a study found that nicotinamide adenine dinucleotide (NAD+) levels decline with age, which may cause cell damage and may shorten lifespan. NAD+ acts as an enzyme cofactor and substrate for a variety of regulatory proteins in many important biological pathways. A large number of studies have shown that increasing NAD+ levels in tissues or cells can slow the aging process. The safety and efficacy of NAD+ have been clinically studied. There is evidence that supplementing NAD+ precursors or inhibiting NAD+ degradation may enhance metabolic activity. Studies have shown that supplementing NAD+ precursors can slow the aging process in mice. To date, the anti-aging properties of NAD+ have not been confirmed in humans. The role of NAD+ in neurodegenerative diseases Several articles mentioned that NAD+ depletion has been observed in both normal and accelerated aging. Neurodegeneration is seen in several accelerated aging diseases, including a ...
Read More
Telmisartan Telmisartan (Micardis) is an oral prescription medication most commonly used to treat hypertension, including mild hypertension where blood pressure is only moderately elevated or borderline. If choosing to self-medicate for mild hypertension or borderline high blood pressure, telmisartan is an excellent or even best choice. As elevated blood pressure is often an undesired side effect of anabolic steroid cycles and can even limit use of androgens, this use of telmisartan is already enough to make the drug of value to many. However, telmisartan also has an entirely different category of use, due to having quite a number of other interesting properties which can be valuable in some instances. I don’t know of a term to describe this second category of use. The closest is a category I call “metabolic healing,” though that’s not a scientific term, in which I’ve been working to develop new administrations of natural product compounds. This has been an ongoing process I haven’t yet completed, but to me it’s extremely promising. What I mean by this category is, use of substances or combinations of substances to change gene expression in a way working to correct damages in gene exp ...
Read More
Sildenafil Citrate Tablets is the composition of the tablets belonging to the brand Dilfil which is used for treating erectile dysfunction (impotence) in adult men. When the penis of the adult man is not suitable for sexual activity. The medication also helps in treating pulmonary hypertension (high blood pressure in the lungs), The composition of the medication is effective only for treating the problems of the adult men and not effective for the newborns, children, as well as for the women. The composition of Sildenafil Citrate Tablets helps in relaxing the blood vessels in the penis of adult men. When the man is sexually active then the medication helps the blood to flow in the penis. The composition of the medication shows its effectiveness only if the man is sexually active. The erectile dysfunction in the male is treated with the help of the composition of the tablet. The medication only helps the man in getting sexually active but the medication does not protect the person from sexually transmitted diseases including AIDS. Uses Of Sildenafil Citrate Tablets The composition of the medication is effective only for men. The medication helps in treating erectile dysfunction in adult m ...
Read More
Description Oxandrolone (Anavar) Anavar or Oxandrolone is a structurally altered dihydrotestosterone (DHT) hormone. This alteration greatly increases the anabolic activity of the hormone and prevents it from being broken down by metabolism. Oxandrolone is highly anabolic and mildly androgenic, so it helps build strength and may promote muscle growth without many adverse side effects. Anavar A steroid is a synthetic testosterone that, when combined with the right diet and exercise, increases muscle mass, builds strength, and reduces body fat. Anavar is popular among beginners and women because its side effects are few and mild. Oxandrolone Dosing: The correct Anavar dosage also depends on whether you are using it for weight loss or weight gain. Anavar cycles vary for both men and women, and for the most part, you should reserve this compound for your cutting cycle. Men can combine testosterone with Deca Durabolin or other anabolic steroids to enjoy a synergistic effect. Doses start at 50 mg to 100 mg of Anavar (Oxandrolone). To increase muscle mass, men can take up to 120 mg of Anavar per day, and can choose to add Trenbolone or Deca Durabolin to the mix. The recommended duration ...
Read More
1. Uses of the drug Raloxifene Raloxifene is a selective estrogen receptor modulator that has very estrogen-like effects in some tissues such as bone, with no effect in other tissues such as breast and uterus. Raloxifene has many uses, which can be listed as follows: Maintains bone density may have other benefits for postmenopausal women Effective in shrinking uterine fibroids Prevents treatment of postmenopausal osteoporosis Menstruation Slows bone loss and helps keep bones strong, less likely to break Reduces the risk of certain types of breast cancer after menopause though. Raloxifene is not an estrogen hormone but acts like estrogen in certain parts of the body such as bones. In contrast to other parts of the body (womb and breasts), Raloxifene acts as an estrogen inhibitor. Raloxifene belongs to a class of drugs called selective estrogen receptor modulators (SERMs), but does not relieve menopausal symptoms. Note Raloxifene is not used before menopause and is not used to prevent heart disease. Raloxifene is usually indicated in the following cases: Treatment and prevention of osteoporosis in postmenopausal women Prevention and treatment of osteoporosis-related vertebral fractures in postmenopausal women, but is us ...
Read More
What is Tadalafil? Tadalafil (generic Cialis) is an FDA-approved medication for erectile dysfunction (ED). It is also used to treat an enlarged prostate (benign prostatic hyperplasia). The medication is FDA-approved for the treatment of pulmonary arterial hypertension (PAH). As mentioned above, it belongs to a class of medications called PDE5 inhibitors. PDE5 inhibitors are compounds that block the action of PDE5, an enzyme that blocks blood vessels. This enzyme does this by breaking down cGMP, a molecule that causes smooth muscle to relax. These actions (blocking the action of PDE5 and preventing the breakdown of cGMP) help PDE5 inhibitors control conditions like erectile dysfunction (ED). It also enables all medications like Tadalafil to treat high blood pressure in the lungs (PAH). In addition to this, studies have shown that daily use of Tadalafil has the potential to increase lean body mass in non-obese men, possibly by enhancing insulin secretion, lowering estradiol, and improving endothelial function in the body. It has also shown potential as a treatment for bronchial asthma. How does tadalafil work? It works by blocking the breakdown of cGMP, an enzyme that promotes muscle relaxation and ...
Read More
Introduction to Super Vilitra Super Vilitra 20mg is a medication specifically designed to address two prevalent male sexual health issues: erectile dysfunction (ED) and premature ejaculation (PE). "Dapoxetine modifies the serotonin transporter, enhancing control over ejaculation by delaying the ejaculatory reflex. Super Vilitra pills provide a complete treatment for adult men with both ED and PE when taken one to three hours before planned sexual activity. Indogenmed is a reliable supplier of Generic Super Vilitra tablets, offering real pharmaceutical medicines and expert support for sexual dysfunction." How Does it Works Super Vilitra Tablets, which combines Dapoxetine and Vardenafil, treats PE and ED in adult men. To understand its mechanism, study its active ingredients' pharmacological characteristics. In addition, Dapoxetine 60 mg, an SSRI, reduces early ejaculation by altering central nervous system neurotransmitter levels. Too much serotonin reuptake reduces neurotransmitter levels, which accelerates ejaculation by inhibiting serotonin reuptake. Dapoxetine enhances synaptic cleft activity. This increased serotonin levels improve ejaculatory control and lengthen the IELT.Super Vilitra tr ...
Read More
Unlike traditional weight loss methods, Smart Brothers 5-Amino-1MQ uses scientific breakthroughs to naturally boost metabolic performance, effectively focusing on reducing fat cells while protecting valuable muscle mass. Enjoy the benefits of Smart Brothers 5-Amino-1MQ 60 capsules package: – Enhances fat burning – Speeds up metabolism – Enhances insulin sensitivity – Lowers cholesterol levels – Promotes rapid weight loss – Controls appetite 5-Amino-1MQ peptide activates key pathways associated with lipolysis and thermogenesis, thereby increasing fat burning capacity, even during rest. It also helps regulate appetite, helping you maintain a healthy diet. Savor the benefits of Smart Brothers 5-Amino-1MQ: – Rapid Fat Dissolution: Achieve your weight loss desire faster – Muscle Mass Preservation: Protect your muscle integrity while removing excess fat – Boost Metabolism: Naturally boost metabolism and increase daily calorie expenditure – Enhanced Vitality: Say goodbye to fatigue and stay energized to fuel your daily tasks and workouts – Appetite Control: Control your hunger and ensure easy adherence to your diet plan ...
Read More
Unlike traditional weight loss methods, Smart Brothers 5-Amino-1MQ uses scientific breakthroughs to naturally boost metabolic performance, effectively focusing on reducing fat cells while protecting valuable muscle mass. Enjoy the benefits of Smart Brothers 5-Amino-1MQ 60 capsules package: – Enhances fat burning – Speeds up metabolism – Enhances insulin sensitivity – Lowers cholesterol levels – Promotes rapid weight loss – Controls appetite 5-Amino-1MQ peptide activates key pathways associated with lipolysis and thermogenesis, thereby increasing fat burning capacity, even during rest. It also helps regulate appetite, helping you maintain a healthy diet. Savor the benefits of Smart Brothers 5-Amino-1MQ: – Rapid Fat Dissolution: Achieve your weight loss desire faster – Muscle Mass Preservation: Protect your muscle integrity while removing excess fat – Boost Metabolism: Naturally boost metabolism and increase daily calorie expenditure – Enhanced Vitality: Say goodbye to fatigue and stay energized to fuel your daily tasks and workouts – Appetite Control: Control your hunger and ensure easy adherence to your diet plan ...
Read More
Stanozolol Ingredients Stanozolol is a derivative of dihydrotestosterone, but doctors generally consider its activity and reaction time to be milder than androgens. You can feel it showing a greater tendency to muscle growth compared to androgenic activity. Stanozolol does provide the best muscle growth, and at the same time, the anabolic properties in this ingredient are mild compared to other compounds. Usually people feel their muscles become firmer and they remain so after stopping the use of stanozolol. You can use a protein-rich diet to keep your muscles getting leaner and firmer. Structure of Stanozolol When you talk about the structure of stanozolol, you will find that it has a structure that cannot be converted into estrogen. With stanozolol, you do not need to worry about water retention caused by estrogen because stanozolol provides a perfect physique and perfect muscles. When you do not want muscle growth to lead to excessive weight, you will find this drug very useful in increasing the raw mass of muscles. Athletes use this anabolic steroid because of its excellent qualities. Dosage of Stanozolol The dosage of stanozolol for men and women varies greatly. The dosage for men is usually 20 to 100 m ...
Read More
Description Oxandrolone (Anavar) Anavar or Oxandrolone is a structurally altered dihydrotestosterone (DHT) hormone. This alteration greatly increases the anabolic activity of the hormone and prevents it from being broken down by metabolism. Oxandrolone is highly anabolic and mildly androgenic, so it helps build strength and may promote muscle growth without many adverse side effects. Anavar A steroid is a synthetic testosterone that, when combined with the right diet and exercise, increases muscle mass, builds strength, and reduces body fat. Anavar is popular among beginners and women because its side effects are few and mild. Oxandrolone Dosing: The correct Anavar dosage also depends on whether you are using it for weight loss or weight gain. Anavar cycles vary for both men and women, and for the most part, you should reserve this compound for your cutting cycle. Men can combine testosterone with Deca Durabolin or other anabolic steroids to enjoy a synergistic effect. Doses start at 50 mg to 100 mg of Anavar (Oxandrolone). To increase muscle mass, men can take up to 120 mg of Anavar per day, and can choose to add Trenbolone or Deca Durabolin to the mix. The recommended duration ...
Read More
Anadrol (Oxymetholone) Anadrol (oxymetholone) is most likely second only to Dianabol (methandrostenolone) as a bodybuilding anabolic steroid. Additionally, it has had considerable medical importance particularly for treatment of anemia, and more recently to help maintain lean body mass in HIV-compromised patients. While many have the subjective opinion that Anadrol is a harsh drug in terms of side effects, medical findings and the findings of many athletes are quite different. Stacking Anadrol with Other Steroids An interesting further question concerns combination of Anadrol with other anabolic steroids. For exmaple, adding Anadrol to 50 mg/day of Dianabol gives little added benefit to a steroid cycle; in contrast, adding Anadrol to 50-100 mg/day trenbolone acetate or 60-80 mg/day Anavar (oxandrolone) gives dramatic improvement. In this its stacking behavior is similar to that of Dianabol, but not to that of trenbolone. Likely this is because unlike trenbolone, oxymetholone does not bind strongly to the androgen receptor, and most of its anabolic effect is likely not genomically mediated via the AR. Anadrol Side Effects With regard to harsh side effects someti ...
Read More
Anadrol (Oxymetholone) Anadrol (oxymetholone) is most likely second only to Dianabol (methandrostenolone) as a bodybuilding anabolic steroid. Additionally, it has had considerable medical importance particularly for treatment of anemia, and more recently to help maintain lean body mass in HIV-compromised patients. While many have the subjective opinion that Anadrol is a harsh drug in terms of side effects, medical findings and the findings of many athletes are quite different. Stacking Anadrol with Other Steroids An interesting further question concerns combination of Anadrol with other anabolic steroids. For exmaple, adding Anadrol to 50 mg/day of Dianabol gives little added benefit to a steroid cycle; in contrast, adding Anadrol to 50-100 mg/day trenbolone acetate or 60-80 mg/day Anavar (oxandrolone) gives dramatic improvement. In this its stacking behavior is similar to that of Dianabol, but not to that of trenbolone. Likely this is because unlike trenbolone, oxymetholone does not bind strongly to the androgen receptor, and most of its anabolic effect is likely not genomically mediated via the AR. Anadrol Side Effects With regard to harsh side effects s ...
Read More
Dianabol (Methandrostenolone) by Bill Roberts – Dianabol (methandrostenolone, methandienone) has been one of the most important anabolic steroids in bodybuilding ever since its introduction in 1958. Also commonly known as “Dbol”, this oral compound is best used for steroid cycles in combination with injectable steroids, but can be of value used alone as well. Stacking Dianabol with Injectable Steroids The effect of most injectable anabolic steroids is greatly enhanced by addition of Dianabol. The improvement is greater than from simply increasing the amount of injectable by the same amount. A classic and dramatic example is trenbolone. Though the total amount of steroid used is the same in all three cases, 50 mg/day each of trenbolone acetate stacked with 50 mg/day Dianabol provides a far more effective steroid cycle than either 100 mg/day of trenbolone acetate alone or 100 mg/day Dbol alone. The side effect profile is superior as well. In other words, the compounds act synergistically: the whole is greater than the parts. This is likely due to differing mechanisms of action. Dianabol and Testosterone Stack All injectables stack well with Diana ...
Read More
Telmisartan Telmisartan (Micardis) is an oral prescription medication most commonly used to treat hypertension, including mild hypertension where blood pressure is only moderately elevated or borderline. If choosing to self-medicate for mild hypertension or borderline high blood pressure, telmisartan is an excellent or even best choice. As elevated blood pressure is often an undesired side effect of anabolic steroid cycles and can even limit use of androgens, this use of telmisartan is already enough to make the drug of value to many. However, telmisartan also has an entirely different category of use, due to having quite a number of other interesting properties which can be valuable in some instances. I don’t know of a term to describe this second category of use. The closest is a category I call “metabolic healing,” though that’s not a scientific term, in which I’ve been working to develop new administrations of natural product compounds. This has been an ongoing process I haven’t yet completed, but to me it’s extremely promising. What I mean by this category is, use of substances or combinations of substances to change gene expression in a way working to correct damages in gene ...
Read More
T3 (liothyronine) T3 (triiodothyronine, liothyronine, Cytomel) is a thyroid hormone drug fairly commonly used for fat loss, particularly in the context of anabolic steroid cycles. T3 is naturally produced in the body as a result of T4 (thyroxine) production by the thyroid. Oral administration of T3 can yield higher levels of serum T3 than would occur naturally, allowing faster fat loss and in some cases potentially greater GH production and greater anabolism. The problem of instability of T3 The first thing to consider about dosing of T3 is that the drug itself has poor stability, resulting in loss of potency with time even with some tabletted pharmaceutical products. Liquid preparations are even more prone to loss of potency. Dosings given below refer to fully potent T3, as found with US-made or European pharmaceutical products still within expiration date. In many instances, other T3 products will contain less or even much less T3 than the label may indicate. For this reason, I recommend seeking out genuine pharmaceutical T3, preferably of American or European origin. Otherwise, dosing can be uncertain or deceptive. For example, a person might find “150 mcg” per day to be an appropriat ...
Read More
Ephedrine Hydrochloride While no longer legal for sale as a dietary supplement in most countries, ephedrine is the most effective herbal fat loss substance ever sold. It’s still worth talking about however, because it’s still available for worldwide shipping from some countries and is still as effective as ever. How Does Ephedrine Relate To Ephedra And Ephedra Alkaloids? Ephedra is a genus of plants which includes numerous species. Some, such as E. sinica, E. equisetina, and E. intermedia contain ephedra alkaloids in amounts sufficient to be useful for fat loss, and are collectively called Ma Huang. Others do not. Ephedra alkaloids are a group of compounds which includes not only ephedrine but several other compounds such as norephedrine and methylephedrine. Legitimate ephedra extracts of the past contained multiple such alkaloids in varying ratios. Of these, ephedrine is the most important for fat loss, but is not the only active compound. While pure ephedrine can be isolated from ephedra alkaloids, synthetic ephedrine is more economical and is by far the predominant type. Generally pure ephedrine is provided as ephedrine HCl or ephedrine sulfate, with no impo ...
Read More
DNP (Dinitrophenol) DNP (dinitrophenol) is a synthetic chemical product which can induce very rapid fat loss when taken orally. It accomplishes this by strongly or even dangerously increasing body temperature and metabolic rate. I have to rate DNP as the harshest and most dangerous drug used in bodybuilding. Although one might think such a drug would be used principally by the highly advanced and elite, this has not been my experience. Generally, these bodybuilders achieve their condition without DNP; the product instead tends to be a crutch for those needing a crutch. In no case do I think better condition is achieved with DNP than are obtainable without it but with proper planning and execution of diet, training, and use of other drugs if any. That said, DNP is a compound that nonetheless sees considerable use and if nothing else, is a product which is remarkable for its fast fat-loss results. History of DNP use for fat loss DNP was first used for fat loss in the 1930s, with the most prominent DNP doctor of the day administering 350 mg/day, and commercial products typically providing 100 mg per capsule. An estimated 100,000 people used DNP during this period; ...
Read More
Clenbuterol Clenbuterol (Spiropent) is a beta-receptor agonist drug used in the treatment of asthma and in bodybuilding for the purpose of fat loss. In some instances, it can also be used to enhance performance in endurance exercise. When to use clenbuterol Clenbuterol should only be used when fat loss needs to be particularly accelerated over a relatively short period of time. For example, if the need or intent is to lose only 1 lb of fat per week, then there are better means to do this than to use clenbuterol. Where fat loss efforts are already maximized or near-maximized, however, clenbuterol use can add perhaps another 1 lb per week to the rate of loss. Dosage and cycling of clenbuterol The effective dose range of clenbuterol extends from 20 mcg/day as a minimum value to 40-140 mcg/day as more common values. I think it best to start at 40 mcg/day and evaluate results on an ongoing basis, increasing dose by 20 mcg at a time as necessary. Many users adjust dosage to the level where the hands begin to shake, but fat loss can be improved markedly with doses well below this point. Clenbuterol should be cycled rather than used continuously or for ...
Read More
Albuterol (Salbutamol) If an improved ephedrine were available, would bodybuilders and those desiring fat loss want it? For many that’s an obvious yes, and albuterol is their improved ephedrine. Albuterol’s Mode Of Fat-Loss Action One of the most effective means of promoting rapid fat loss is activation (agonism) of beta-adrenergic receptors. Beta receptor activation increases lipolysis and metabolic rate, and can decrease appetite. All these work to improve fat loss. Prior to changes in the law, the most widely used means of doing this had been with ephedrine. The most hardcore way has been with clenbuterol. Perhaps the best way, for most, is with albuterol. Medically, albuterol is used to improve breathing of asthmatics and patients with chronic obstructive pulmonary disease. Safe initial dosing is typically 2-4 mg taken three to four times per day. (Higher dosings are needed only with time, as downregulation occurs.) The same dosing levels can also be effective for fat loss, for maintenance of muscle during fat loss, and often for significant increase in endurance performance and/or slight increase in strength. Another positive effect of ...
Read More
